.. pyaging documentation master file, created by
sphinx-quickstart on Sun Nov 19 17:35:20 2023.
This file is the entry point to the pyaging package documentation.
.. raw:: html
.. raw:: html
.. image:: https://img.shields.io/badge/docs-latest-brightgreen.svg?style=flat
:target: https://pyaging.readthedocs.io/en/latest/?badge=latest
:alt: Documentation Status
.. image:: https://img.shields.io/pypi/v/pyaging.svg
:target: https://pypi.python.org/pypi/pyaging
:alt: PyPI version
.. image:: https://img.shields.io/github/license/lucascamillomd/pyaging.svg
:target: https://github.com/lucascamillomd/pyaging/blob/main/LICENSE
:alt: License
.. image:: https://img.shields.io/badge/DOI-10.1093%2Fbioinformatics%2Fbtae200-blue.svg
:target: https://doi.org/10.1093/bioinformatics/btae200
:alt: DOI
.. raw:: html
pyaging
=======
.. raw:: html
GPU-accelerated biological aging clocks in Python — 170+ published clocks across DNA methylation, histone marks, ATAC-seq, RNA-seq, and blood chemistry, behind a one-line prediction API.
.. grid:: 2 2 4 4
:gutter: 3
:class-container: sd-text-center
.. grid-item-card:: :octicon:`rocket;1.5em;sd-text-primary` Get started
:link: tutorials/tutorial_dnam_illumina_human_array
:link-type: doc
Install pyaging and run your first prediction — the Illumina 450K/EPIC walkthrough.
.. grid-item-card:: :octicon:`telescope;1.5em;sd-text-primary` Clock Catalogue
:link: clock_glossary
:link-type: doc
Filter, sort, and search every available clock.
.. grid-item-card:: :octicon:`beaker;1.5em;sd-text-primary` Tutorials
:link: tutorials/index
:link-type: doc
End-to-end walkthroughs for each data type.
.. grid-item-card:: :octicon:`mark-github;1.5em;sd-text-primary` GitHub
:link: https://github.com/lucascamillomd/pyaging
Source, issues, and contributions.
Why pyaging
-----------
.. grid:: 1 1 3 3
:gutter: 3
.. grid-item-card:: 170+ clocks
A comprehensive, curated collection of published aging clocks, each cross-validated against its source.
.. grid-item-card:: Multi-omic
DNA methylation, histone marks, ATAC-seq, RNA-seq, and blood chemistry — one consistent interface.
.. grid-item-card:: GPU-optimized
A PyTorch backend runs predictions on CPU or GPU with no code changes.
.. image:: ../_static/pyaging_graphical_abstract.png
:align: center
:alt: pyaging graphical abstract
:class: pyaging-abstract
.. raw:: html
.. toctree::
:hidden:
:caption: Getting Started
installation
clock_glossary
.. toctree::
:hidden:
:caption: Tutorials
tutorials/index
.. toctree::
:hidden:
:caption: API Reference
pyaging
.. toctree::
:hidden:
:caption: Clock implementation
clock_implementation